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Knockdown of a Specific Circular Non-coding RNA Significantly Suppresses Osteosarcoma Progression Article

Shidong Wang, Hongliang Zhang, Bo Li, Chenglong Chen, Tingting Ren, Yi Huang, Kai Liu, Jingjing Li, Wei Guo

Engineering 2023, Volume 21, Issue 2,   Pages 187-193 doi: 10.1016/j.eng.2021.12.007

Abstract: Abnormally expressed non-coding circular RNAs (circRNAs) are crucial for the occurrence and development

Keywords： Non-coding RNA     Osteosarcoma     CircRNA     Molecular mechanism     Knockdown    

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Ribozyme and the mechanisms that underlie RNA catalysis

Timothy J. Wilson,Yijin Liu,David M. J. Lilley

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 2,   Pages 178-185 doi: 10.1007/s11705-016-1558-2

Abstract: Ribozymes are widespread, and catalyze some extremely important reactions in the cell. Mechanistically most fall into one of two classes, using either metal ions or general acid-base catalysis. The nucleolytic ribozymes fall into the latter class, mostly using nucleobases. A sub-set of these use a combination of guanine base plus adenine acid to catalyze the cleavage reaction. New ribozymes are still being discovered at regular intervals and we can speculate on the potential existence of ribozymes that catalyze chemistry beyond phosphoryl transfer reactions, perhaps using small-molecule coenzymes.

Keywords： RNA catalysis     RNA structure     catalytic mechanism    

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Tumor-Specific CircRNA-Derived Antigen Peptide Identification for Hepatobiliary Tumors Article

Wenwen Wang, Lili Ma, Zheng Xing, Tinggan Yuan, Jinxia Bao, Yanjing Zhu, Xiaofang Zhao, Yan Zhao, Yali Zong, Yani Zhang, Siyun Shen, Xinyao Qiu, Shuai Yang, Hongyang Wang, Dong Gao, Peng Wang, Lei Chen

Engineering 2023, Volume 22, Issue 3,   Pages 159-170 doi: 10.1016/j.eng.2022.06.008

Abstract: In this study, we aimed to investigate the potential of circular RNAs (circRNAs) as a novel source ofUsing RNA-sequencing (RNA-seq) with an algorithm-based score tool, 3950 translated tumor-specific circRNAs

Keywords： Tumor antigen     Patient-derived hepatobiliary tumor organoid     Circular RNA     Mass-spectrometry-based immunopeptidomics    

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LEVERAGING LIVESTOCK TO PROMOTE A CIRCULAR FOOD SYSTEM

Zhengxia DOU

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 1,   Pages 188-192 doi: 10.15302/J-FASE-2020370

Abstract: animal-derived food is slowing while attention is growing over the role of livestock farming in an enhanced circular
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Anti RNA Viruses Related Biomaterials

Yao Kangde,Yin Yuji,Zhang Baolian,Zhao Liguo

Strategic Study of CAE 2003, Volume 5, Issue 7,   Pages 17-23

Abstract:

The structure, reproduction, replication and transcription of RNA viruses were introduced.Antivirus strategies including design of anti - SARS drugs, RNA interference, DNA vaccine delivery systemThese examples imply the interactions of RNA viruses with proteins, DNA, and polysaccharides.

Keywords： Anti-RNA viruses     protein     DNA     polysaccharide     biomaterials    

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RNA-Based Biocontrols—A New Paradigm in Crop Protection Review

Matthew Bramlett, Geert Plaetinck, Peter Maienfisch

Engineering 2020, Volume 6, Issue 5,   Pages 522-527 doi: 10.1016/j.eng.2019.09.008

Abstract: Over the last years, the RNA interference (RNAi) process has been identified as a very promising newRNA-based active ingredients (AIs) possess a unique mode of action and can be implemented via both geneticRNA-based AIs promise to deliver the selectivity and sustainability desired in future crop protectionresearch progress toward RNA-based biocontrols against the Colorado potato beetle (CPB), corn rootwormMany challenges still exist on the road to the implementation of a broad range of RNA-based products

Keywords： RNA-based biocontrols     RNA interference (RNAi)     Colorado potato beetle (CPB)     Corn rootworm (CRW)     Soy    

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LEVERAGING LIVESTOCK TO PROMOTE A CIRCULAR FOOD SYSTEM

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 1,

Abstract: animal-derived food is slowing while attention is growing over the role of livestock farming in an enhanced circular
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Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages

LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 166-170 doi: 10.1007/s11684-008-0030-1

Abstract: Murine Rip2 small interfering RNA (siRNA) plasmids were constructed and transfected into macrophage and
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Overexpressed long noncoding RNA CRNDE with distinct alternatively spliced isoforms in multiple cancers

Xuefei Ma, Wei Zhang, Rong Zhang, Jingming Li, Shufen Li, Yunlin Ma, Wen Jin, Kankan Wang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 330-343 doi: 10.1007/s11684-017-0557-0

Abstract: CRNDE is a long noncoding RNA with alternative splicing and is implicated in the pathogenesis of several

Keywords： long noncoding RNA     CRNDE     alternative splicing    

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Circular economy：ideas and innovation

Jin Yong,Feng Zhijun,Chen Dingjiang

Strategic Study of CAE 2010, Volume 12, Issue 1,   Pages 4-11

Abstract: "text-align: justify;">It has been over a decade since China paid close attention to the concept of circularDuring this period the country made promoting circular economy as one of the basic national developmentimportant ideas and theories, which could be used as general guidelines for innovation to boost the circular

Keywords： circular economy     circular economics    

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Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide

Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 502-508 doi: 10.1007/s11684-017-0590-z

Abstract: In this review, the RNA virion-like particles of hepatitis B virus (HBV) are integrated into the lifecycle of HBV replication, and the potential significance of serum HBV RNA is systematically describedThe production of HBV RNA virion-like particles should not be blocked by NA; in this regard, serum HBVRNA is found to be a suitable surrogate marker for the activity of intrahepatic covalently closed circular, with pregenomic RNA origination, can only be transcribed from cccDNA.

Keywords： chronic hepatitis B     serum HBV RNA     nucleos(t)ide analogs     virological response     para-functional cure    

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immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq

Frontiers of Medicine doi: 10.1007/s11684-023-1017-7

Abstract: By conducting single-cell RNA-seq analyses on 26 gliomas, we reported their classification into primitive

Keywords： single-cell RNA-seq     glioma     radial glia     primitive oligodendrocyte precursor cell     immune escape    

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Construction and identification of lentiviral RNA interference vector of rat leptin receptor gene

Zhengjuan LIU, Jie BIAN, Yuchuan WANG, Yongli ZHAO, Dong YAN, Xiaoxia WANG

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 57-60 doi: 10.1007/s11684-009-0003-z

Abstract: The aim of the present study was to construct the lentiviral RNA interference (RNAi) vector of rat OBRb

Keywords： receptors     leptin     RNA interference     lentivirus vector    

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Frequencies of circular plate with concentric ring and elastic edge support

Lokavarapu Bhaskara RAO,Chellapilla Kameswara RAO

Frontiers of Mechanical Engineering 2014, Volume 9, Issue 2,   Pages 168-176 doi: 10.1007/s11465-014-0299-5

Abstract:

Exact solutions for the flexural vibrations of circular plates having elastic edge conditions alongValues of frequency parameter for the considered circular plate are computed for different sets of valuesrotational and linear restraints and the radius of the rigid ring support on the vibration behavior of circular

Keywords： circular plate     frequency     elastic edge     rigid ring     mode switching    

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RNA m6A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 481-489 doi: 10.1007/s11684-018-0654-8

Abstract:

N6-methyladenosine (m6A) is the most common post-transcriptional RNAmodification throughout the transcriptome, affecting fundamental aspects of RNA metabolism. m6

Keywords： RNA modification     m6A     immunity     cancer     epigenetics    

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Title Author Date Type Operation

Knockdown of a Specific Circular Non-coding RNA Significantly Suppresses Osteosarcoma Progression

Shidong Wang, Hongliang Zhang, Bo Li, Chenglong Chen, Tingting Ren, Yi Huang, Kai Liu, Jingjing Li, Wei Guo

Journal Article

Ribozyme and the mechanisms that underlie RNA catalysis

Timothy J. Wilson,Yijin Liu,David M. J. Lilley

Journal Article

Tumor-Specific CircRNA-Derived Antigen Peptide Identification for Hepatobiliary Tumors

Wenwen Wang, Lili Ma, Zheng Xing, Tinggan Yuan, Jinxia Bao, Yanjing Zhu, Xiaofang Zhao, Yan Zhao, Yali Zong, Yani Zhang, Siyun Shen, Xinyao Qiu, Shuai Yang, Hongyang Wang, Dong Gao, Peng Wang, Lei Chen

Journal Article

LEVERAGING LIVESTOCK TO PROMOTE A CIRCULAR FOOD SYSTEM

Zhengxia DOU

Journal Article

Anti RNA Viruses Related Biomaterials

Yao Kangde,Yin Yuji,Zhang Baolian,Zhao Liguo

Journal Article

RNA-Based Biocontrols—A New Paradigm in Crop Protection

Matthew Bramlett, Geert Plaetinck, Peter Maienfisch

Journal Article

LEVERAGING LIVESTOCK TO PROMOTE A CIRCULAR FOOD SYSTEM

Journal Article

Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages

LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao

Journal Article

Overexpressed long noncoding RNA CRNDE with distinct alternatively spliced isoforms in multiple cancers

Xuefei Ma, Wei Zhang, Rong Zhang, Jingming Li, Shufen Li, Yunlin Ma, Wen Jin, Kankan Wang

Journal Article

Circular economy：ideas and innovation

Jin Yong,Feng Zhijun,Chen Dingjiang

Journal Article

Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide

Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia

Journal Article

immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq

Journal Article

Construction and identification of lentiviral RNA interference vector of rat leptin receptor gene

Zhengjuan LIU, Jie BIAN, Yuchuan WANG, Yongli ZHAO, Dong YAN, Xiaoxia WANG

Journal Article

Frequencies of circular plate with concentric ring and elastic edge support

Lokavarapu Bhaskara RAO,Chellapilla Kameswara RAO

Journal Article

RNA m6A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Journal Article